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Welcome to The Psychiatry Letter, the source for independent, scientifically sound psychiatric education. PL was published as a monthly newsletter on mental health and psychopharmacology from 2016-2019. This site provides new content on clinical cases and studies, as well as access to shopping for e-books and other resources (click Shop above). Visit the original newsletter site here to read all archived issues for free and use the index there to get access to topics of interest.

Nassir Ghaemi MD

Jun 7
1 min

PL Reflections

In the PL newsletter, aphorisms or brief comments were included as PL Reflections. Here in this column, the new PL website will continue ...

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Nassir Ghaemi MD

Jun 7
14 min

Curbside Questions: Brief answers to clinical queries

6/7/2020 Question: How would PL approach this case and what does it think of the plan taken? A 14 year old female is in the midst of a ...

602 views9 comments

Nassir Ghaemi MD

Jun 7
3 min

Becoming a psychiatrist: Harvard residency notes

Back in 1991-1994, I attended my psychiatry residency at McLean Hospital, the preeminent training program in the Harvard system at the t...

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Nassir Ghaemi MD

Mar 7
5 min

What did Kraepelin teach? Was he wrong?

Psychiatric clinicians don't tend to know their history, or if they do, it's often superficial. A classic example is the work of Emil Kr...

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Nassir Ghaemi MD

Feb 6
1 min

Tylenol: Avoid it in pregnancy?

A new study was just published in JAMA Psychiatry providing prospective evidence of an an association between tylenol (acetaminophen) use...

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Nassir Ghaemi MD

Nov 5, 2019
3 min

Chronic fatigue: What causes it?

A 37 year-old man with hypertension reports fatigue since mid-adolescence, and a depressive episode one year earlier. He did not do well w...

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Nassir Ghaemi MD

Oct 22, 2019
2 min

Polypharmacy after post-stroke depression

One way of understanding brain laterality and mood is that when one side is disabled, the other side becomes more active. In general, act...

103 views2 comments

Nassir Ghaemi MD

Oct 7, 2019
3 min

Was Kraepelin right?

The classic diagnostic validators in psychiatry are symptoms, course of illness, genetics, and biological markers. Treatment response or ...

240 views2 comments

Nassir Ghaemi MD

Sep 28, 2019
2 min

Gynecomastia with antipsychotics

Question: A 33 year old male patient with autism spectrum disorder has developed mild gynecomastia (without galactorrhea, but with slight...

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Nassir Ghaemi MD

Sep 27, 2019
1 min

Suicide prevention with lithium or clozapine?

Question: A colleague told me that lithium only prevents suicide in bipolar illness, while clozapine prevents suicide in schizophrenia. I...

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Nassir Ghaemi MD

Sep 27, 2019
3 min

Agitation with mirtazapine

Question: A patient in his early 60s who is a university professional had depression, anxiety and associated irritable bowel syndrome. As...

172 views2 comments

All e-books are half-price.

Visit our store now!

PL Reflections

Curbside Questions: Brief answers to clinical queries

Becoming a psychiatrist: Harvard residency notes

What did Kraepelin teach? Was he wrong?

Tylenol: Avoid it in pregnancy?

Chronic fatigue: What causes it?

Polypharmacy after post-stroke depression

Was Kraepelin right?

Gynecomastia with antipsychotics

Suicide prevention with lithium or clozapine?

Agitation with mirtazapine

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