The First PL Webinar Course has ended:

Advanced Psychopharmacology

Stay tuned for a repeat of this course in the fall and a new course on Diagnosis and Psychopathology. Subscribe above to be notified when these new courses are available, planned for registration from mid-September 2021 to December 1 2021.

Welcome to The Psychiatry Letter, the source for independent, scientifically sound psychiatric education. PL was published as a monthly newsletter on mental health and psychopharmacology from 2016-2019. This site provides new content on clinical cases and studies, as well as access to shopping for e-books and other resources (click Shop above).

All e-books are half-price.

Visit our store now!

Please note our new email address: (not .com)

Also, the original PL website will be migrated to this website in the coming months ( will no longer function)

Nassir Ghaemi MD

May 31
7 min

Research and Practice: Twins, not Opposites

I never have understood clinicians who see clinical research as unrelated or even opposed to what they do. This attitude – that clinical...

189 views0 comments

Nassir Ghaemi MD

May 3
2 min

Suicide and lithium skeptics

Question: In sharing with a colleague your textbook on Psychopharmacology, she pointed out that for lithium to have any anti-suicidal...

368 views2 comments

Nassir Ghaemi MD

Apr 8
4 min

How to keep up with the literature

[This essay was written in response to psychiatric residents at Tufts Medical Center who requested advice on how to keep up with the...

1,037 views1 comment

Nassir Ghaemi MD

Feb 27
8 min

Becoming a psychiatrist: Harvard residency notes

Back in 1991-1994, I attended my psychiatry residency at McLean Hospital, the preeminent training program in the Harvard system at the...

1,146 views0 comments

Nassir Ghaemi MD

Jan 22
19 min

Curbside Consults

Q: I have a 37-year-old woman with chronic depression since adolescence. She seems to have a baseline of mild depression with 1-2...

1,210 views9 comments

Nassir Ghaemi MD

Jun 7, 2020
1 min

PL Reflections

In the PL newsletter, aphorisms or brief comments were included as PL Reflections. Here in this column, the new PL website will continue...

541 views2 comments

Nassir Ghaemi MD

Mar 7, 2020
5 min

What did Kraepelin teach? Was he wrong?

Psychiatric clinicians don't tend to know their history, or if they do, it's often superficial. A classic example is the work of Emil...

495 views0 comments

Nassir Ghaemi MD

Feb 6, 2020
1 min

Tylenol: Avoid it in pregnancy?

A new study was just published in JAMA Psychiatry providing prospective evidence of an an association between tylenol (acetaminophen) use...

486 views0 comments

Nassir Ghaemi MD

Nov 5, 2019
3 min

Chronic fatigue: What causes it?

A 37 year-old man with hypertension reports fatigue since mid-adolescence, and a depressive episode one year earlier. He did not do well...

280 views0 comments

Polypharmacy after post-stroke depression

Subscribe to Our Site

The First PL Webinar Course has ended:

Advanced Psychopharmacology

Stay tuned for a repeat of this course in the fall and a new course on Diagnosis and Psychopathology. Subscribe above to be notified when these new courses are available, planned for registration from mid-September 2021 to December 1 2021.

All e-books are half-price.

Visit our store now!

Please note our new email address: info@psychiatryletter.net (not .com)

Also, the original PL website will be migrated to this website in the coming months (www.psychiatryletter.com will no longer function)

Research and Practice: Twins, not Opposites

Suicide and lithium skeptics

How to keep up with the literature

Becoming a psychiatrist: Harvard residency notes

Curbside Consults

PL Reflections

What did Kraepelin teach? Was he wrong?

Tylenol: Avoid it in pregnancy?

Chronic fatigue: What causes it?

Please note our new email address: (not .com)

Also, the original PL website will be migrated to this website in the coming months ( will no longer function)